A 42 year old woman presents with oligomenorrhea for 2 years, and 30 kg of weight gain during the same period, even though her diet remained unchanged.
Her medical history is significant for type 2 diabetes, hypertension and dyslipidemia for 3 years; while well controlled initially, these have worsened over the last year. She is currently on Metformin, Gliclazide, Telmisartan, and Rosuvastatin.
Her family history is significant for polycystic ovarian disease in a sister. She only drinks socially and does not smoke.
A full blood count is within normal parameters, as are serum electrolytes, and renal and liver profiles. A thyroid profile and serum FSH, LH, testosterone, and growth hormone levels are also normal.