Dry

A 45 year old woman presents with a dry mouth, and difficulty in eating, speaking, and swallowing for 5 months.

She also complains of burning and itching of her eyes, along with a foreign body sensation.

Her medical and drug histories are unremarkable. There is no history of sexual promiscuity.

Select Relevant Investigations
Ocular Surface Staining

Performed

The ocular staining score is 3
Lip biopsy

Performed

A biopsy is obtained from the lower lip and associated salivary glands. The lip shows focal periductal and mononuclear cell infiltrate with acinar cell loss in the labial minor salivary glands.
Antibody screening

Performed

Anti-Ro (Anti-SSA) antibodies: positive
Anti-La (Anti-SSB) antibodies: positive
Rheumatoid Factor: negative
Antinuclear Antibodies: negative
Parotid Sialometry

Performed

Unstimulated whole saliva flow: 0.05 ml/min (normal: < 0.1 ml/min)

Select Relevant Management
Tear Replacement
Parotidectomy
Immunosuppression
Pilocarpine